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Revista Practica Farmaceutica, Vol. 7, Nr. 4 (24), 2014
ISSN 2066-5563  |  e-ISSN 2069-6671
ISSN-L 2066-5563
DOI: 10.37897/RJPhP

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Actualitati si perspective privind cercetarea rezistentei multimedicamentoase în farmacoterapia afectiunilor sistemului nervos central

, and

INTRODUCERE

În ciuda eforturilor enorme, obţinerea unui profil de concentrare în condiţii de siguranţă şi eficacitate în creier rămâne una dintre cele mai mari provocări pentru descoperirea şi dezvoltarea de medicamente destinate sistemului nervos central (SNC). Deşi există mai multe motive, multe eşecuri sunt datorate subestimării complexităţii creierului şi, de asemenea, a farmacocineticii (PK) specific la acest nivel.

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